Chao Qi, Sofia Lovestam, Alexey G Murzin, Sew Peak-Chew, Catarina Franco, Marika Bogdani, Caitlin Latimer, Jill R Murrell, Patrick W Cullinane, Zane Jaunmuktane, Thomas D Bird, Bernardino Ghetti, Sjors HW Scheres, Michel Goedert.
Tau filaments with the Alzheimer fold in human MAPT mutants V337M and R406W.
Nature Structural & Molecular Biology (2025).
Chao Qi, Ryota Kobayashi, Shinobu Kawakatsu, Fuyuki Kametani, Sjors HW Scheres, Michel Goedert, Masato Hasegawa.
Tau filaments with the chronic traumatic encephalopathy fold in a case of Vacuolar Tauopathy with VCP mutation D395G.
Acta Neuropathologica (2024).
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors HW Scheres, Michel Goedert.
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold.
Proceedings of the National Academy of Sciences (2023).
Chao Qi, Masato Hasegawa, Masaki Takao, Motoko Sakai, Mayasuki Sasaki, Masashi Mizutani, Akio Akagi, Yasushi Iwasaki, Hiroaki Miyahara, Mari Yoshida, Sjors HW Scheres, Michel Goedert.
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.
Acta Neuropathologica Communications (2023).
Chao Qi, Pia Lavriha, Erva Bayraktar, Anand Vaithia, Dina Schuster, Micaela Pannella, Valentina Sala, Paola Picotti, Mario Bortolozzi, Volodymyr M Korkhov.
Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Science Advances (2023).
Chao Qi, Silvia Acosta-Gutierrez, Pia Lavriha, Alaa Othman, Diego Lopez-Pigozzi, Erva Bayraktar, Dina Schuster, Paola Picotti, Nicola Zamboni, Mario Bortolozzi, Francesco L Gervasio, Volodymyr M. Korkhov.
Structure of the connexin-43 gap junction channel reveals a closed sieve-like molecular gate.
eLife (2023).
Chao Qi, Pia Lavriha, Ved Mehta, Basavraj Khannpnavar, Inayathulla Mohammed, Yong Li, Michalis Lazaratos, Jonas V. Schaefer, Birgit Dreier, Andreas Plückthun, Ana-Nicoleta Bondar, Carmen W. Dessauer, Volodymyr M. Korkhov.
Structural basis of adenylyl cyclase 9 activation.
Nature Communications (2022).
Chao Qi, Simona Sorrentino, Ohad Medalia, Volodymyr M. Korkhov.
The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science (2019).
Chao Qi, Giulio Di Minin, Irene Vercellino, Anton Wutz, Volodymyr M. Korkhov.
Structural basis of sterol recognition by human hedgehog receptor PTCH1.
Science Advances (2019).
Na Feng*, Chao Qi*, Yan-jie Hou, Ying Zhang, Da-Cheng Wang, De-Feng Li.
The C2'- and C3'-endo equilibrium for AMP molecules bound in the cystathionine-beta-synthase domain.
Biochemical and Biophysical Research Communications (2018).
Chao Qi, De-Feng Li, Lei Feng, Yanjie Hou, Hui Sun, Da-Cheng Wang, Wei Liu.
Biochemical and structural characterization of a novel ubiquitin-conjugating enzyme E2 from Agrocybe aegeria reveals Ube2w family-specific properties.
Scientific Reports (2015).
B. Khannpnavar*, V. Mehta*, Chao Qi*, V. Korkhov.
Structure and function of adenylyl cyclases, key enzymes in cellular signaling.
Current Opinion in Structural Biology (2020).
Pia Lavriha, Chao Qi, Volodymyr M Korkhov.
Expression, purification, and nanodisc reconstitution of Connexin-43 hemichannels for structural characterization by cryo-EM.
Methods in Molecular Biology (2024).
Pia Lavriha, Yufei Han, Xinyue Ding, Dina Schuster, Chao Qi, Anand Vaithia, Paola Picotti, Volodymyr M Korkhov.
Mechanism of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate.
PLoS One (2024).
Basavraj Khanppnavar, Julian Maier, Freja Herborg, Ralph Gradisch, Erika Lazzarin, Dino Luethi, Jae-Won Yang, Chao Qi, Marion Holy, Kathrin Jaentsch, Oliver Kudlacek, Klaus Schicker, Thomas Werge, Ulrik Gether, Thomas Stockner, Volodymyr Korkhov, Harald H Sitte.
Structural basis of organic cation transporter-3 inhibition.
Nature Communications (2022).
Xuefeng Zhang, Alejandro Pizzoni, Kyoungja Hong, Nyla Naim, Chao Qi, Volodymyr Korkhov, Daniel L Altschuler.
CAP1 binds and activates adenylyl cyclase in mammalian cells.
Proceedings of the National Academy of Sciences (2021).
F. Cannac, Chao Qi, J Falschlunger, G Hausmann, K Basler, VM Korkhov.
Cryo-EM structure of the Hedgehog release protein Dispatched.
Science Advances (2020).
X. Q. Xie, X-L Zhang, Chao Qi, D-F Li, Joy Fleming, D-C Wang, L-J Bi.
Crystallographic observation of the movement of the membrane-distal domain of the T7SS core component EccB1.
Acta Crystallographica F (2016).
Li-Li Miao, Yan-Jie Hou, Hong-Xia Fan, Jie Qu, Chao Qi, Ying Liu, De-Feng Li, Zhi-Pei Liu.
Molecular structural basis for the cold adaptedness of the psychrophilic β-glucosidase BglU.
Applied and Environmental Microbiology (2016).